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The Influence of Honey-flavored Yogurt on Low-grade Inflammation and Gut Health in Middle to Older Aged Women.
Sponsor: University of California, Davis
Summary
A randomized, double-blind, crossover dietary intervention trial will test the effects of 4 weeks of daily honey-flavored yogurt intake on markers of inflammation (Th17 cytokines) and oxidative stress (NOX2, UA, RSNO) and associative changes with microbial derived metabolites (SCFAs, BAs, ellagitannins), metabolism and the fecal microbiome. The above suite of selected markers will capture diet-induced systemic changes in inflammation and oxidative stress, while assessing associated microbial changes.
Key Details
Gender
FEMALE
Age Range
45 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2021-11-01
Completion Date
2026-07-31
Last Updated
2026-02-10
Healthy Volunteers
Yes
Conditions
Interventions
Honey sweetened yogurt
2 tbsp. of daily honey intake in 1.2 cups of yogurt per day, split into two equal portions
Sugar sweetened yogurt
sugar added, in an isocaloric fashion to the honey, to 1.2 cups of yogurt per day, split into two equal portions
Locations (1)
University of California, Davis; Department of Nutrition
Davis, California, United States