Clinical Research Directory

Inclusion Criteria: * • Cohort A: Any adult who is presenting with controlled disproportionate breathlessness will be considered for inclusion as a diseased subject (with excluded comorbidities as cause of breathlessness e.g. uncontrolled asthma (GINA 2019 guidelines), uncontrolled cardiac disease, ILO). * Cohort B: Any adult who is in good respiratory health will be considered for inclusion as a normal in the study. Exclusion Criteria: * Subject unable to sit in an upright position for required period * Subjects with significant co morbidities (assessed by the clinician at screening only): * Chest wall or spinal deformity e.g. scoliosis OSA, Apnoea hypopnoea index \> 30 (if known) * Any other significant disease or disorder which, in the opinion of the investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participants' ability to participate in the study * BMI \> 40 * Height \> 194 cm * Female participant who is pregnant, lactating or planning pregnancy during the course of the study * Inability to consent/comply with trial protocol