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Spontaneous Antigenemia in Loiasis
Sponsor: Washington University School of Medicine
Summary
This prospective study will enroll and follow 60 loiasis patients with high worm burden to monitor the spontaneous release of filarial antigen in peripheral blood. This study will define the cross-reactive antigen profile of persons with spontaneous loiasis antigenemia, and determine whether it varies with time.
Official title: Spontaneous Antigenemia in Loiasis, A Study of the Loiasis Antigens Responsible for Cross-reactivity in the Rapid Diagnostic Test for Lymphatic Filariasis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
86
Start Date
2020-01-23
Completion Date
2021-05-31
Last Updated
2026-08-21
Healthy Volunteers
No
Conditions
Interventions
No intervention
Patients in these cohorts will not be given anti-filariasis therapies because these drugs are not approved for use in patients with high worm burdens (\>20,000 Mf/mL)
Locations (1)
Centre for Research on Filariasis and other Tropical Diseases (CRFilMT)
Yaoundé, Cameroon