Clinical Research Directory

Inclusion Criteria: * Damaged or diseased corneal endothelium from Fuchs' or PBK * Willingness to commit to required study visits Exclusion Criteria: * Prior Endothelial Keratoplasty (EK) or any other surgery except uncomplicated cataract surgery * Presence of a condition that increases the probability for treatment failure (e.g., heavily vascularized cornea, uncontrolled uveitis) * Other primary endothelial dysfunction conditions (e.g., posterior polymorphous corneal dystrophy and congenital hereditary corneal dystrophy, iridocorneal endothelial syndrome) * Central sub-epithelial or stromal scarring that could impact post-operative clarity assessment * Peripheral anterior synechiae in the angle greater than 3 clock hours * Hypotony * Uncontrolled glaucoma * Visually significant optic nerve or macular pathology