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Proximal Row Carpectomy vs Four-corner Fusion for Osteoarthritis of the Wrist
Sponsor: Töölö Hospital
Summary
Study purpose is to compare the outcome after proximal row carpectomy (PRC) vs four-corner fusion (FCA) for SLAC/SNAC II-III type osteoarthritis (OA) in a double-blinded randomized controlled study setting. Patients with radiologically and clinically confirmed OA are randomized (1:1 computer generated sequence with random block size) to two parallel groups and will undergo either PRC or FCA. The study will be patient and assessor blinded. Baseline data is collected preoperatively and is followed by a follow-up visits at 2 and 6 weeks, 3, 6, 12 months, and 5, 10 years after the intervention. Unveiling of the allocation is at 12 months post-intervention.
Official title: A Double-blinded Randomized Controlled Multicenter Trial Comparing Proximal ROw carpectOmy and Four-corner Fusion (PROOF) for Osteoarthritis of the Wrist
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
84
Start Date
2020-10-01
Completion Date
2034-12-31
Last Updated
2021-01-19
Healthy Volunteers
No
Interventions
Proximal Row Carpectomy
Excision of the proximal carpal row - the scaphoid, lunate and triquetrum
Four-corner fusion
Scaphoid excision and four-corner fusion with cannulated headless compression screws/dorsal plate
Locations (5)
Töölö Hospital (Helsinki University Hospital)
Helsinki, Finland
Central Hospital of Central Finland
Jyväskylä, Finland
Kymenlaakso Central Hospital
Kotka, Finland
Tampere University Hospital
Tampere, Finland
Turku University Hospital
Turku, Finland