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ACTIVE NOT RECRUITING
NCT04261972

Cell-free DNA in Hereditary And High-Risk Malignancies 1

Sponsor: University Health Network, Toronto

View on ClinicalTrials.gov

Summary

The goal of this study is to develop an effective, sensitive blood test that can detect early tumours in patients with known or suspected hereditary cancer syndromes (HCS). If this new blood test is accurate, it could be used to screen patients for cancer and allow for earlier cancer detection. The study will also use questionnaires and interviews to understand how patients feel about incorporating these tests into routine medical care, and the perceptions of the medical value of test results.

Official title: Early Detection of Cancer in High-risk Patients Through Cell-free DNA 1

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1416

Start Date

2018-07-01

Completion Date

2026-12-31

Last Updated

2026-01-14

Healthy Volunteers

No

Interventions

GENETIC

Next generation sequencing (NGS)

NGS

Locations (7)

BC Cancer Agency

Vancouver, British Columbia, Canada

Eastern Health

St. John's, Newfoundland and Labrador, Canada

IWK Health Centre

Halifax, Nova Scotia, Canada

Sinai Health System

Toronto, Ontario, Canada

University Health Network

Toronto, Ontario, Canada

Women's College Hospital

Toronto, Ontario, Canada

Jewish General Hospital

Montreal, Quebec, Canada