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Cell-free DNA in Hereditary And High-Risk Malignancies 1
Sponsor: University Health Network, Toronto
Summary
The goal of this study is to develop an effective, sensitive blood test that can detect early tumours in patients with known or suspected hereditary cancer syndromes (HCS). If this new blood test is accurate, it could be used to screen patients for cancer and allow for earlier cancer detection. The study will also use questionnaires and interviews to understand how patients feel about incorporating these tests into routine medical care, and the perceptions of the medical value of test results.
Official title: Early Detection of Cancer in High-risk Patients Through Cell-free DNA 1
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1416
Start Date
2018-07-01
Completion Date
2026-12-31
Last Updated
2026-01-14
Healthy Volunteers
No
Conditions
Interventions
Next generation sequencing (NGS)
NGS
Locations (7)
BC Cancer Agency
Vancouver, British Columbia, Canada
Eastern Health
St. John's, Newfoundland and Labrador, Canada
IWK Health Centre
Halifax, Nova Scotia, Canada
Sinai Health System
Toronto, Ontario, Canada
University Health Network
Toronto, Ontario, Canada
Women's College Hospital
Toronto, Ontario, Canada
Jewish General Hospital
Montreal, Quebec, Canada