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RECRUITING
NCT04263285
NA

Treatment of Depression Post-SCI

Sponsor: Medical University of South Carolina

View on ClinicalTrials.gov

Summary

Depression is more common after a spinal cord injury (SCI) than in the general population. Unfortunately, it is unknown how depression is typically treated in individuals with SCI or if commonly used treatment methods are effective. This study will investigate the safety and impact of a novel method for treating depression called repetitive transcranial magnetic stimulation (rTMS). rTMS is a type of non-invasive brain stimulation. Fourteen individuals with a cervical or thoracic level SCI and depression will complete an approved treatment plan using rTMS. Participants will be treated using rTMS five days a week for four weeks. After four weeks of treatment, the study team will review the safety of rTMS and assess changes in depressive symptoms. If the results are positive, larger studies can be designed to develop better treatment options for individuals with SCI and depression.

Official title: Treatment of Depression Post-SCI: Retrospective Analysis and Feasibility Trial

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

14

Start Date

2026-10

Completion Date

2029-09

Last Updated

2026-03-04

Healthy Volunteers

No

Interventions

DEVICE

rTMS

The study team will deliver rTMS five days a week for four weeks, according to a specific and approved protocol for participant positioning, motor threshold determination, and dosing.

Locations (1)

Medical University of South Carolina

Charleston, South Carolina, United States