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Cognitive Prefrail and Frailty, and Motoric Cognitive Risk Syndrome: Prevalence and Association With Incident Adverse Health Events
Sponsor: Jewish General Hospital
Summary
We defined a new and early condition in the spectrum of cognitive frailty: the "cognitive-prefrailty" which is a combination of prefrailty stage and subjective cognitive impairment (SCI). This study aims to: (1) examine and compare the prevalence of cognitive-prefrailty, cognitive frailty and motoric cognitive risk syndrome (MCR) syndromes in participants of the Canadian Longitudinal Study of Aging (CLSA) using the (tracking and comprehensive) baseline assessment, (2) examine the association of cognitive-prefrailty, cognitive frailty and MCR syndromes with incident adverse health events using the information collected during the first CLSA 18-month follow-up, and (3) compare the criteria performances (i.e., sensitivity, specificity, positive predictive value, negative predictive value, area under receiver operating characteristic curve, positive and negative likelihood ratio) for incident adverse health events of the cognitive-prefrailty, cognitive frailty and MCR syndromes.
Official title: Cognitive Prefrail and Frailty, and Motoric Cognitive Risk Syndrome: Prevalence and Association With Incident Adverse Health Events in the Canadian Longitudinal Study on Aging
Key Details
Gender
All
Age Range
45 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
30000
Start Date
2020-12-01
Completion Date
2025-02-01
Last Updated
2024-04-05
Healthy Volunteers
Yes
Interventions
Data collection
Telephone interview questionnaire, in-home face-to-face interview, and data from the Collection Site
Locations (1)
Jewish General Hospital
Montreal, Quebec, Canada