Clinical Research Directory

* Inclusion Criteria: 1. Patient can be of any gender; 2. Patient must be admitted to the ED with a traumatic closed head injury within 72 hours of injury; 3. Patient's Age must be ≥18 and \<86 years old at time of enrollment; 4. Patient must be Glasgow Coma Scale (GCS) 14-15 at time of BrainScope evaluation (even if GCS was lower prior to arrival e.g. at time of injury). * Exclusion Criteria: 1. Patients with forehead, scalp, earlobe or skull abnormalities or other conditions that would prevent correct application of the electrode headset; 2. Patients with Dementia, Parkinson's Disease, Multiple Sclerosis, brain tumors, history of brain surgery, evidence of acute psychosis or history of stroke with neurological deficit within the last year; 3. Patients on anti-platelets, anti-coagulants, other than aspirin, currently receiving dialysis or in end-stage renal disease or current condition is "critical" in the opinion of the investigator; 4. Patients with active fever defined as greater than 100oF or 37.7oC; 5. Patients suffering from an open head injury or have suffered multi-trauma which requires hospitalization (for injuries not related to the head injury) 6. Patients requiring advanced airway management (i.e. mechanical ventilation); 7. Patients currently receiving procedural sedation medications (e.g. benzodiazepine, anesthetic, NMDA receptor antagonist, or opioid agonist) Note: patient can be enrolled when they are no longer obtunded and have the capacity to consent; 8. Pregnant women and prisoners; 9. Patients who have had a Head CT scan for current traumatic injury event prior to screening.