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Effects of a Specific Substance in Smokers
Sponsor: Oregon Health and Science University
Summary
Although rates of cigarette use are declining, the proportion of nondaily smokers is rising, particularly among young adults. Among young adults, nondaily smoking is associated with negative health consequences and, for some, may lead to the establishment of life-long smoking patterns. The goal of this project is to understand the behavioral, psychological and neurobiological factors that contribute to cigarette use in nondaily smokers to aid the development of tailored evidence-based interventions.
Official title: An MRI Study of Neural Activity Following Exposure to a Specific Substance in Young Cigarette Smokers
Key Details
Gender
All
Age Range
21 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2020-02-25
Completion Date
2025-12-31
Last Updated
2025-07-28
Healthy Volunteers
Yes
Conditions
Interventions
Study Agent
The study agent will be administered via beverages and/or a capsule. The substances used in the study are legal, non-prescription, and are proven safe for human consumption at the doses used. The study agent may be a depressant (such as alcohol), a stimulant (such as caffeine), or an analgesic (such as aspirin).
Placebo
In the placebo conditions participants will consume beverages and capsules that contain no or very small quantities of the study agent.
Locations (1)
Oregon Health and Science University
Portland, Oregon, United States