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NCT04283539

Identification of Pathways to Mitigate Immune-Related Adverse Events With Cancer Immunotherapy

Sponsor: National Jewish Health

View on ClinicalTrials.gov

Summary

This protocol is a prospective, observational study of participants receiving immunotherapy (checkpoint inhibitors, CPI) for cancer therapy, testing the hypothesis that patients with immune related cutaneous adverse events (ircAEs) have unique immunologic endotypes associated with polarized immune responses.

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

OBSERVATIONAL

Enrollment

255

Start Date

2020-09-23

Completion Date

2026-02-28

Last Updated

2026-06-16

Healthy Volunteers

No

Interventions

DRUG

systemic corticosteroid or biologic

Treatment with systemic corticosteroids or biologic therapies (for corticosteroid refractory patients or these in which corticosteroids are not the treatment of choice)

Locations (3)

National Jewish Health

Denver, Colorado, United States

The Melanoma and Skin Cancer Institute

Denver, Colorado, United States

Memorial Sloan Kettering Cancer Center

New York, New York, United States