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Memory Retrieval and Encoding Investigated by Neural Stimulation
Sponsor: University of Pennsylvania
Summary
The purpose of this research is to understand biomarkers of human memory through correlational analyses and to use focal electrical stimulation as a causal manipulation to understand how biomarkers of memory relate to other brain states and behavioral measures.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
800
Start Date
2014-10-12
Completion Date
2024-12-31
Last Updated
2024-11-05
Healthy Volunteers
No
Conditions
Interventions
Direct electrical stimulation
Stimulation will not exceed 0.75 mA and will be approved prior by study investigators. Each subject will have a safety threshold testing at the beginning of each session and if 'afterdischarges' occur the subject's stimulation threshold will be lowered.
Locations (11)
University of Colorado, Denver
Aurora, Colorado, United States
Emory University Hospital
Atlanta, Georgia, United States
National Institute of Neurological Disorders and Stroke
Bethesda, Maryland, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Mayo Clinic
Rochester, Minnesota, United States
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States
Columbia University
New York, New York, United States
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States
UT Southwestern Medical Center
Dallas, Texas, United States
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States