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Multi-Centre Observational Study of Maintenance Niraparib in Treatment of Ovarian CanceR
Sponsor: Royal Marsden NHS Foundation Trust
Summary
This is a multi-centre, observational (non-interventional) study, designed to follow patients with advanced ovarian fallopian tube and primary peritoneal cancer, who are receiving Niraparib as maintenance treatment, according to the Niraparib access criteria (via TESARO patient access programme, EMA licence and NHS pending NICE assessment due 2018) including assessment of tolerability to Niraparib therapy.
Official title: Multi-Centre Observational Study of Maintenance Niraparib in Treatment of Ovarian CanceR: UK Routine Clinical Practice Experience
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
388
Start Date
2020-02-03
Completion Date
2026-04-24
Last Updated
2026-05-13
Healthy Volunteers
No
Interventions
Niraparib
Niraparib - Niraparib is an oral, highly selective PARP-1 and -2 inhibitor. However, it also inhibits other members of the PARP family, including PARP 3, -4, -10, 12, -14, and -15\[13\].
Locations (15)
Royal United Hospitals Bath
Bath, United Kingdom
Belfast Health & Social Care Trust
Belfast, United Kingdom
University Hospitals Birmingham NHS Foundation Trust
Birmingham, United Kingdom
University Hospitals Bristol NHS Foundation Trust
Bristol, United Kingdom
Addenbrookes Hospital
Cambridge, United Kingdom
Velindre Cancer Centre, Velindre University NHS Trust
Cardiff, United Kingdom
Morecambe Bay NHS Trust
Lancaster, United Kingdom
St James's University Hospital
Leeds, United Kingdom
Barts Health NHS Trust
London, United Kingdom
Northampton General Hospital NHS Trust
Northampton, United Kingdom
Mount Vernon Cancer Centre, East and North Hertfordshire NHS Trust
Northwood, United Kingdom
Queen's Hospital
Romford, United Kingdom
University Hospital Southampton NHS Foundation Trust
Southampton, United Kingdom
Royal Marsden NHS Foundation Trust
Sutton, United Kingdom
Royal Cornwall Hospitals NHS Trust
Truro, United Kingdom