Clinical Research Directory
Browse clinical research sites, groups, and studies.
No Axillary sUrgical Treatment In Clinically Lymph Node Negative Patients After UltraSonography
Sponsor: Seoul National University Hospital
Summary
NAUTILUS study is a prospective, multicenter, RCT. Clinically T1,T2, node negative BCS candidates with no evidence of metastases in AUS are 1:1 randomized into no SLNB group and SLNB group. NAUTILUS study aim to establish the minimally invasive treatment of breast cancer by reexamining the necessity of sentinel lymph node biopsy among patients with invasive breast cancer who have tumors under 5cm, are clinically node-negative, and are having breast conserving surgery performed.
Official title: No Axillary sUrgical Treatment In Clinically Lymph Node Negative Patients After UltraSonography[NAUTILUS]: A Prospective, Multicenter, Phase III Clinical Trial
Key Details
Gender
FEMALE
Age Range
19 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1734
Start Date
2020-09-15
Completion Date
2027-12-31
Last Updated
2026-02-13
Healthy Volunteers
No
Conditions
Interventions
No SLNB
BCS only. Ommission of SLNB by axilla ultrasonography among selective breast cancer patients
SLNB
BCS with SLNB(+/-ALND)
Locations (1)
Seoul National University Hospital
Seoul, Seoul, South Korea