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Research for the Molecular Imaging of the PD-L1 Targeting Tracer
Sponsor: Peking University Cancer Hospital & Institute
Summary
To use the molecular probe PET radionuclide (Ga-68 or F-18) WL12 peptide to detect the expression of PD-L1 in the primary and metastatic lesions in patients with solid tumor; to detect the expression heterogeneity of PD-L1 in the lesion and inter-lesions; to observe the change of PD-L1 expression in the course of treatment. To provide an approach for screening patients with high expression of PD-L1, efficacy monitoring, drug resistance and early warning of recurrence and metastasis to achieve the Individualized antitumor treatment of targeted drugs.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2019-08-06
Completion Date
2024-12
Last Updated
2024-08-19
Healthy Volunteers
No
Conditions
Interventions
18F-WL12 PET or 68Ga-WL12 PET
WL12, labeled with PET radio-nuclide ( Ga-68 or F-18)will be used as a molecular imaging tracer for PET/CT scanning
Locations (1)
Shunlian Zhou
Beijing, China