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Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity
Sponsor: Medical University of Vienna
Summary
Objective: To compare the effects of volatile and intravenous anesthetics on pupillary function after general anesthesia using a portable infrared pupillometer. Design: A monocentric, prospective, double blinded randomized study. Patients: Patients who require elective Ear, Nose and Throat (ENT) surgery under general anesthesia. Interventions: Patients undergoing elective ENT surgery will be assigned to intravenous versus inhalative anesthesia and pupillometric parameters monitored postoperative, using an infrared pupillometer. Outcomes measures: Reported pupillometric parameters after intravenous and inhalative anesthesia. The purpose of this study is to compare general anesthesia techniques (volatile, intravenous) on postoperative changes in pupillary reactivity by using infrared pupillometry.
Official title: Infrared Pupillometry - Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
108
Start Date
2020-03-09
Completion Date
2026-03-10
Last Updated
2025-07-04
Healthy Volunteers
No
Conditions
Interventions
PLR
PLR measurements will be performed within the first 2 postoperative hours.
Alertness testing
Preoperative (baseline) and every 30 minutes postoperative computer based alertness testing will be performed.
Propofol anesthesia
Maintenance of anesthesia will be performed using propofol.
Sevoflurane anesthesia
Maintenance of anesthesia will be performed using sevoflurane.
Locations (1)
Medical University Vienna
Vienna, Vienna, Austria