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Hormone Replacement Trial Against ALzheimers' Disease
Sponsor: University Hospital, Ghent
Summary
The influence of postmenopausal hormone treatment on dementia is not clear. Dysfunctions in the metabolism of amyloid in the disease of Alzheimer result in an elevated presence of degradation products in cerebrospinal fluid. The degradation products in blood will be analysed during the trial, to get better insight in menopause and the start of hormonal therapy. Postmenopausal women with and without history of breast cancer will be recruited for the trial.
Key Details
Gender
FEMALE
Age Range
40 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
600
Start Date
2018-04-17
Completion Date
2028-12-31
Last Updated
2025-01-27
Healthy Volunteers
Yes
Conditions
Interventions
blood take
Blood is taken to analyse degradation products of the metabolism of amyloid
Locations (1)
Ghent university hospital
Ghent, Belgium