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ACTIVE NOT RECRUITING
NCT04318977
NA

rTMS Add on Value for Amelioration of Negative Symptoms of Schizophrenia

Sponsor: University of Regensburg

View on ClinicalTrials.gov

Summary

Treatment of depression with repetitive transcranial magnetic stimulation (rTMS) has shown high evidence using high-frequency left dorsolateral prefrontal cortex (DLPFC) stimulation. The treatment of negative symptoms with the same protocol in schizophrenia is considered as possible effective. Theta burst stimulation is a new protocol which is characterized by shorter sessions showing first evidence that it's efficacy is comparable to the high-frequency rTMS. In this randomized placebo-controlled study the efficacy of high-frequency rTMS and TBS are evaluated.

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

62

Start Date

2020-02-01

Completion Date

2025-12-30

Last Updated

2025-09-19

Healthy Volunteers

No

Interventions

DEVICE

high-frequency rTMS

repetitive transcranial magnetic stimulation

DEVICE

TBS

theta burst stimulation

DEVICE

placebo

placebo transcranial magnetic stimulation

Locations (4)

Brno University Hospital

Brno, Czechia

University Hospital Ostrava

Ostrava, Czechia

University Hospital Aachen

Aachen, Germany

University of Regensburg

Regensburg, Germany