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rTMS Add on Value for Amelioration of Negative Symptoms of Schizophrenia
Sponsor: University of Regensburg
Summary
Treatment of depression with repetitive transcranial magnetic stimulation (rTMS) has shown high evidence using high-frequency left dorsolateral prefrontal cortex (DLPFC) stimulation. The treatment of negative symptoms with the same protocol in schizophrenia is considered as possible effective. Theta burst stimulation is a new protocol which is characterized by shorter sessions showing first evidence that it's efficacy is comparable to the high-frequency rTMS. In this randomized placebo-controlled study the efficacy of high-frequency rTMS and TBS are evaluated.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
62
Start Date
2020-02-01
Completion Date
2025-12-30
Last Updated
2025-09-19
Healthy Volunteers
No
Interventions
high-frequency rTMS
repetitive transcranial magnetic stimulation
TBS
theta burst stimulation
placebo
placebo transcranial magnetic stimulation
Locations (4)
Brno University Hospital
Brno, Czechia
University Hospital Ostrava
Ostrava, Czechia
University Hospital Aachen
Aachen, Germany
University of Regensburg
Regensburg, Germany