Clinical Research Directory

Inclusion Criteria: 1. Participants from the Biobank (Molecular and Imaging Studies of Cardiovascular Health and Disease) cohort in Singapore, who agreed to be contacted for further studies 2. Male and female patients older than 21 years 3. Willingness to participate and ability to provide informed consent Exclusion Criteria: 1. Patients with exclusion criteria for the MRI, such as: 1. implanted devices (surgical clips, heart pacemakers or defibrillators, cochlear implants) 2. iron-based tattoos 3. any other pieces of metal or devices that are not MR-Safe anywhere in the body 4. patients who exhibit noticeable anxiety and/or claustrophobia into the MRI scanner 2. Pregnant women 3. Diagnosis of heart failure NYHA classes III and IV 4. Impaired renal function with eGFR\<45 ml/min or proteinuria \> 0.5 g/24h 5. Liver disease with cirrhosis (Child-Pugh class C) or hypoalbuminemia 6. Peripheral oedema as assessed by the investigator 7. Active cancer 8. Patients who have received an organ or bone marrow transplant 9. Patients who have had major surgery in the past 3 months 10. Patients who have severe comorbid conditions likely to compromise survival or study participation 11. Unwillingness or other inability to cooperate