Clinical Research Directory

Inclusion Criteria: * 18-80 years of age. * Crohn's disease with predominantly de novo fibrotic stenosis\* confirmed by endoscopic and radiological tests, accessible by endoscopy (colonoscopy). * Patients with known stenosis previously treated with stenting and/or dilation performed over one year before the date of inclusion. * Symptomatology of intestinal occlusion-subocclusion. * Refractoriness to conventional medical treatment (non-response to the usual accelerated step-up therapeutic approach). * Stenosis length \< 10 cm. * Maximum of 2 stenoses. * Informed consent from patient. Exclusion Criteria: * No informed consent from the patient. * Complicated stenosis with abscess, fistula or significant activity associated with CD not limited to the area of the stenosis. * Patients with known stenosis previously treated with stenting and/or dilation performed \< 1 year before the date of inclusion. * Pregnancy or lactation. * Any clinical situation that prevents the performance of endoscopy or surgery. * Stenosis not accessible by endoscopy. * Asymptomatic patient. * Stenosis length ≥ 10 cm. * Presents with \> 2 stenoses. * Severe coagulation disorders (platelets \< 70000; INR \> 1.8).