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RECRUITING
NCT04332367
PHASE2

Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

Sponsor: Abramson Cancer Center at Penn Medicine

View on ClinicalTrials.gov

Summary

The purpose of this study is to determine if the combination of the three anti-cancer drugs carboplatin, paclitaxel, and ramucirumab is helpful in shrinking tumors or delaying tumor growth in participants with non-small cell lung cancer. This study will also assess whether it is safe to combine these drugs.

Official title: Phase II, Single-Arm Study Of Carboplatin, Weekly Taxane, And Ramucirumab In Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC) After Progressive Disease On Maintenance Pemetrexed And/Or Pembrolizumab

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

59

Start Date

2020-08-01

Completion Date

2026-04

Last Updated

2026-01-07

Healthy Volunteers

No

Interventions

DRUG

Carboplatin

Carboplatin IV

DRUG

Paclitaxel

Paclitaxel IV

DRUG

Ramucirumab

Ramucirumab IV

Locations (1)

Abramson Cancer Center of the University of Pennsylvania

Philadelphia, Pennsylvania, United States