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The Influence of Mitochondrial-Derived Reactive Oxygen Species on Racial Disparities in Neurovascular Function
Sponsor: Auburn University
Summary
Black individuals are at increased cardiovascular disease risk. The central goal of the study is to determine if mitochondrial reactive oxygen species influence blood vessel function and nervous system regulation of blood pressure differentially in black, compared to white individuals. These findings may help to explain a potential mechanism that contributes to racial disparities in blood pressure and cardiovascular disease risk. A secondary goal is to determine if mitochondrial reactive oxygen species improves blood pressure and vascular function in individuals with elevated blood pressure and stage 1 hypertension.
Key Details
Gender
All
Age Range
19 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2020-10-02
Completion Date
2025-08-31
Last Updated
2024-05-29
Healthy Volunteers
Yes
Interventions
MitoQ
Four to eight 20mg capsules (depending on body mass)
Locations (1)
Kinesiology Building
Auburn, Alabama, United States