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Role of the Environment and Endocrine Disruptors in Child Cryptorchidism
Sponsor: University Hospital, Montpellier
Summary
Cryptorchidism is the most frequent congenital defect of the male newborn. It requires surgery in childhood, increases the risk of fertility disorders and cancer. As a major public health objective, it's the subject of numerous recommendations. Its frequency is increasing in some countries faster than a single genetic cause could not explain it. It may occurs in a geographic cluster. The cause of cryptorchidism involves genetic, hormonal and environmental factors. Animal studies suggest that endocrine disruptors interfere with fetal testicular migration. The aim of the study is to find out if some environmental exposition may be associated with cryptorchidism.
Key Details
Gender
MALE
Age Range
1 Month - 18 Years
Study Type
OBSERVATIONAL
Enrollment
1452
Start Date
2020-04-16
Completion Date
2028-04-15
Last Updated
2025-10-03
Healthy Volunteers
No
Conditions
Interventions
Measure of the exposure of parent of male with /without cryptorchidism to endocrine disruptors
Measure of the exposure of parent of patient with/without cryptorchidism to endocrine disruptors (job exposure, during pregnancy)
Locations (1)
University hospital of Montpellier
Montpellier, France