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COMPLETED
NCT04343287
PHASE2/PHASE3

Safety and Efficacy of BRM421 for Dry Eye Syndrome Treatment

Sponsor: BRIM Biotechnology Inc.

View on ClinicalTrials.gov

Summary

The objective of this study is to compare the safety and efficacy of BRM421 Ophthalmic Solution to placebo for the treatment of the signs and symptoms of dry eye.

Official title: A Multi-Center, Randomized, Double Masked, Placebo Controlled Clinical Study to Assess the Safety and Efficacy of BRM421 Ophthalmic Solution in Subjects With Dry Eye Using a Controlled Adverse Environment (CAE®) Model

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

220

Start Date

2020-01-15

Completion Date

2020-06-23

Last Updated

2026-05-01

Healthy Volunteers

No

Interventions

DRUG

BRM421

The active control with BRM421 solution

DRUG

Placebo

The vehicle solution

Locations (4)

Eye Research Foundation

Newport Beach, California, United States

Midwest Cornea Associates, LLC

Indianapolis, Indiana, United States

Andover Eye Associates

Andover, Massachusetts, United States

Total Eye Care

Memphis, Tennessee, United States