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RECRUITING
NCT04343443
NA

Acute Heart Failure With Reduced Ejection Fraction - COngestion Discharge Evaluation

Sponsor: Central Hospital, Nancy, France

View on ClinicalTrials.gov

Summary

The AHF-CODE reduced study is a prospective, non-randomized, monocenter study performed in patients with heart failure with reduced ejection fraction admitted for worsening heart failure. The main objective of the AHF-CODE study is to identify congestion markers (clinical, biological and ultrasound) at the end of hospitalization for acute heart failure that are associated with the risk of all cause death or rehospitalization for acute heart failure within 3 months of hospital discharge.

Official title: Acute Heart Failure With Reduced Ejection Fraction - COngestion Discharge Evaluation: Evaluation de la Congestion à la Sortie d'Hospitalisation Pour Insuffisance Cardiaque aiguë à Fraction d'éjection altérée ou modérément altérée

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2020-08-21

Completion Date

2028-08-21

Last Updated

2023-06-05

Healthy Volunteers

No

Interventions

PROCEDURE

Clinical examination centered on congestion

Clinical examination centered on congestion (ASCEND, NYHA and Ambrosy Score) will be performed before discharge from hospital

PROCEDURE

Cardio-pulmonary, peritoneal, jugular and renal Doppler ultrasounds and liver elastography

Cardio-pulmonary, peritoneal, jugular and renal Doppler ultrasounds and liver elastography will be performed before discharge from hospital

PROCEDURE

Biological: Blood sample retrieved for biological assessment and biobanking

Blood sample collection will be performed before discharge from hospital

PROCEDURE

Telephone interview

Telephone interview will be performed at 3, 12 months and 24 months after discharge from hospital

BEHAVIORAL

Kansas City Cardiomyopathy Questionnaire (KCCQ)

Questionnaire centered on patient's quality of life at discharge and 3, 12 and 24 months after discharge

Locations (1)

CHRU de Nancy

Vandœuvre-lès-Nancy, France