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Evaluating the Immune Response for COVID-19
Sponsor: Assaf-Harofeh Medical Center
Summary
The 2019-20 coronavirus disease, caused by COVID-19, is an ongoing pandemic. The measures in which public health officials quarantine confirmed and isolate symptomatic cases in order to reduce the spread COVID-19 is the common practice used in most countries. However, a significant question remains in regards to the asymptomatically infected individuals, which may propagate the virus and impede infection control. The other question to consider is whether these asymptomatic carriers develop an immune response or continue viral shedding. The purpose of the current study is the evaluate the immune response, i.e developing anti-SARS-CoV-2 antibodies in the asymptomatic cases, in a household study design. We plan to evaluate over 1000 patients with positive COVID-19 results and their households.
Official title: Evaluation of the Immune Response in Symptomatic and Asymptomatic Patients' Diagnosed Witih COVID-19
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
214
Start Date
2020-05-01
Completion Date
2022-02-02
Last Updated
2026-04-21
Healthy Volunteers
Not specified
Conditions
Interventions
COVID-19 RT-PCR
Nasoropharyngeal swabs for COVID-19 RT-PCR - initial screening/retest +every 10 days in 100 days followup period
COVID-19 Serology
Blood samples for COVID-19 serology - initial screening/retest +every 10 days in 100 days followup period Each sample will be examined by 4-6 serology kits.
Symptoms questionnare
Symptoms questionnaire which will be filled by participant on initial screening/retest visit + every 10 days in 100 days followup period
Locations (1)
Assaf-Harofeh Medical Center
Ramla, Israel