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RECRUITING
NCT04353804
NA

Returning to Everyday Tasks Utilizing Rehabilitation Networks-III (RETURN-III)

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

Millions of patients survive care in medical and surgical Intensive Care Units (ICUs) every year, only to suffer from a new or accelerated dementia-like process, called post-ICU long-term cognitive impairment (ICU-LTCI). ICU-LTCI causes considerable problems with personal relationships, return to work, and everyday tasks, such as managing medicines and money. No treatment for these patients is currently available. Technology using computerized cognitive rehabilitation could improve ICU-LTCI by harnessing the healing potential of the brain (i.e., neuroplasticity). This intervention is scalable, portable, and economical. The investigators will evaluate the effectiveness of computerized cognitive rehabilitation in a randomized controlled trial of 160 ICU survivors. The investigators hypothesize that this intervention could improve cognition. This research has high potential to influence rehabilitation strategies for Veteran and civilian ICU survivors.

Official title: Returning to Everyday Tasks Utilizing Rehabilitation Networks-III Pilot Randomized Clinical Trial (RETURN-III Pilot RCT)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

160

Start Date

2022-10-03

Completion Date

2027-07-31

Last Updated

2026-03-13

Healthy Volunteers

No

Interventions

OTHER

Treatment Arm: Computerized Cognitive Rehabilitation

Treatment Arm: Computerized Cognitive Rehabilitation

OTHER

Active Control computer games

Active Control computer games

Locations (2)

Tennessee Valley Healthcare System Nashville Campus, Nashville, TN

Nashville, Tennessee, United States

Vanderbilt University Medical Center

Nashville, Tennessee, United States