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The Olmsted NAFLD Epidemiology Study (TONES)
Sponsor: Mayo Clinic
Summary
Researchers are assessing the prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in the population and assembling a well-characterized cohort of adults with NAFLD and NASH to validate models of NAFLD diagnosis and determine long-term outcomes.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
800
Start Date
2020-10-10
Completion Date
2028-06
Last Updated
2026-01-16
Healthy Volunteers
No
Interventions
Magnetic Resonance Elastography
Combines MRI imaging with sound waves to create a visual map (elastogram) showing the stiffness of body tissues.
Blood draw
Clinical blood tests with a focus on liver function parameters and diabetes
Liver biopsy
If indicated per MRE results a biopsy will be taken of the liver.
Fibro Scan
If indicated per MRE results a fibroscan will be performed of the liver.
Locations (1)
Mayo Clinic in Rochester
Rochester, Minnesota, United States