Clinical Research Directory

Inclusion Criteria: 1. Age 18 to 65 years old 2. Total TBSA of 15% or greater with at least 10% TBSA of third-degree burn 3. Potential need for a skin graft procedure determined by the local burn surgeon 4. Survivable burn injury determined by the admitting local burn surgeon on admission Exclusion Criteria: 1. Non-survivable burn injury determined by the admitting local burn surgeon on admission 2. History of chronic renal failure requiring dialysis prior to injury 3. History of developmental delay or congenital cognitive disorders 4. Prior history of connective tissue disorders or autoimmune disease 5. Anoxic or traumatic brain injury 6. Prior history of cerebrovascular accident with residual mobility impairment 7. Neurologic injury or disease-causing mobility impairment 8. Prior history of leg amputation 9. Non-viable leg requiring amputation on admission 10. Anticipated inability to return for follow up testing after discharge 11. History of a New York Heart Association (NYHA) class IV congestive heart failure