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Early Detection of Familial Hypercholesterolemia in Children
Sponsor: Institut Investigacio Sanitaria Pere Virgili
Summary
Heterozigous FH is an underdiagnosed disease in the paediatric population. Its early detection, would allow us to initiate lifestyle therapeutical changes and early pharmacological therapy if necessary. This is a key fact to reduce atherosclerosis progression and cardiovascular risk in adulthood. Moreover, it will allow, detecting the first and second degree affected relatives.
Official title: Early Detection of Familial Hypercholesterolemia in Children in Tarragona Province
Key Details
Gender
All
Age Range
2 Years - 18 Years
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2013-03-14
Completion Date
2030-07-01
Last Updated
2025-04-18
Healthy Volunteers
No
Conditions
Interventions
lifestyle assessment
A semi-quantitative assessment of the consumption of different food groups will be carried out using a frequency questionnaire validated by the Spanish population27. This questionnaire consists of 137 food items and will be obtained by the dietitian of our Unit (see annex). The child population and/or their parents will be instructed on how to fill the data in the food diary for a period of 3 days, in order to be able to analyse the nutritional composition of the intake and the effect on the lipid profile. The first food register, will be obtained at the collection visit before starting any type of treatment. Another food diary will be included after one year. Physical activity will be collected from the Minnesota Test and we will ask about the consumption of tobacco.
Locations (2)
Hospital Universitari Sant Joan de Reus
Reus, Tarragona, Spain
Hospital Universitari Sant Joan
Reus, Tarragona, Spain