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Study of Metabolic Changes in the Transformation Malignant Precancerous Skin Lesions
Sponsor: University Hospital, Bordeaux
Summary
Skin carcinomas are the most frequent cancers in the world, including basal cell carcinomas and cutaneous squamous cell carcinoma (cSCCs), with more than 60.000 new annual cases in France. Their incidence increases mainly due to ultraviolet (UV) exposure and population ageing. Then from 1994 to 2006, the incidence of cSCC has increased by 300%. CSCCs typically manifests as a spectrum from a precursor actinic keratosis (AK) - possible spontaneous regression at this stage- to in situ cSCC invasive cSCC and finally metastatic cSCC.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
119
Start Date
2020-02-28
Completion Date
2024-06-27
Last Updated
2026-06-24
Healthy Volunteers
No
Interventions
biopsy
Skin biopsies will be performed according to standard practices in the usual aseptic conditions, the operator wearing sterile gloves. A circular knife 3 mm will be used. Procedure interventions do not involve a drug or a device.
Locations (1)
Hôpital Saint-André - CHU de Bordeaux
Bordeaux, France