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Novel Pulmonary Function Measures for Diagnosis of Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem-Cell Transplantation in Children
Sponsor: The Hospital for Sick Children
Summary
In this study, we will study 129Xe-MRI and LCI as tools for diagnosis of BOS in pediatric patients who have received Hematopoietic Stem Cell Transplantation (HSCT) and have been identified as eligible for this study. Participants will be required to have vital signs collected, complete breathing tests and complete an MRI. The MRI will require participants to perform breath holds in the MRI scanner with xenon gas while being coached by a research assistant.
Key Details
Gender
All
Age Range
6 Years - 18 Years
Study Type
OBSERVATIONAL
Enrollment
15
Start Date
2020-10-20
Completion Date
2026-06-30
Last Updated
2026-02-27
Healthy Volunteers
No
Conditions
Locations (1)
The Hospital for Sick Children
Toronto, Ontario, Canada