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Assessment of the Relationship Between Cerebral Blood Flow and Heart Rate
Sponsor: University of Calgary
Summary
The investigators will seek to determine the relationship between heart rate and middle cerebral artery (MCA) cerebral blood flow (CBF), as well as better understand the hemodynamic determinants of MCA CBF velocity. In order to manipulate heart rate, the investigators will recruit patients already scheduled for clinically indicated elective electrophysiological studies, where temporary pacing catheters placed in the right atrium can be used to artificially pace the heart at controlled rates. MCA CBF will be measured by transcranial Doppler ultrasound.
Official title: Assessment of the Relationship Between Cerebral Blood Flow and Heart Rate: An Electrophysiology Based Study
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2021-08-11
Completion Date
2027-06
Last Updated
2024-05-09
Healthy Volunteers
No
Conditions
Interventions
Electrophysiological Pacing
Assess the MCA CBF velocity response at different paced heart rates.
Locations (1)
Foothills Medical Center
Calgary, Alberta, Canada