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Using Cotyledon Perfusion to Study Drugs Transfer Across the Placenta
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
Drug prescriptions are usual during pregnancy however women and their fetuses still remain an orphan population with regard to drugs efficacy and safety clinical studies. Most xenobiotics diffuse through the placenta and some of them can alter fetus development resulting in structural abnormalities, growth or functional deficiencies. The aim of the study is to study the drug transfer using human placenta after delivery.
Official title: Ex Vivo Study of Drugs Transfer Across the Placenta
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2000
Start Date
2020-06-05
Completion Date
2030-06
Last Updated
2025-09-12
Healthy Volunteers
No
Conditions
Interventions
Placenta perfusion
Placenta perfusion in double closed circuit, during 3 hours
Locations (1)
CIC Port-Royal-Cochin
Paris, France