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Sentinel Lymph Node Mapping in Esophageal Cancer Using ICG Dye and NIR Imaging
Sponsor: Memorial Sloan Kettering Cancer Center
Summary
The purpose of this study is to find out whether sentinel lymph node (SLN) mapping with ICG dye and NIR imaging can be used to identify esophageal or esophagogastric junction cancer that has spread to the lymph nodes. If SLN mapping is successful in these types of cancer, surgeons in the future could identify the sentinel lymph nodes and only remove these instead of removing all the lymph nodes which is currently done.
Official title: Does the Concept of the Sentinel Lymph Node Apply to Esophageal Cancer? A Prospective Assessment of Near-infrared Image-guided Lymphatic Mapping and Sentinel Lymph Node Identification in Esophageal Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2020-05-20
Completion Date
2026-05
Last Updated
2025-07-03
Healthy Volunteers
No
Conditions
Interventions
Injection of indocyanine green (ICG)dye
Patients will receive a perilesional injection of indocyanine green (ICG) before the laparoscopic phase of the esophagectomy.
Near-Infrared Image-Guided
Real-time near-infrared (NIR) fluorescence imaging will be performed by use of the Novadaq PINPOINT minimally invasive system with a laparoscopic camera.
Sentinel Lymph Node (SLN) mapping
Any identified SLNs will be dissected during the standard completion lymphadenectomy and esophagectomy.
Locations (1)
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States