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Treatment of Tinnitus With Migraine Medications
Sponsor: University of California, Irvine
Summary
Tinnitus represents one of the most common and distressing otologic problems, and it causes various somatic and psychological disorders that interfere with the quality of life. It is well-understood that many factors, such as poor education, lower income, or occupational, and recreational activity associated with high noise exposure, influences the prevalence and risk of tinnitus. Although the economic and emotional impact of tinnitus is large, there is currently no FDA-approved medication to treat this condition. However, there are pharmacological options to address the stress, anxiety, and depression that are caused by tinnitus. In this project, we intend to use medications for patients with tinnitus in order to decrease the impact of tinnitus on their daily life and activities.
Official title: Treatment of Tinnitus With Migraine Medications: A Randomized Clinical Trial
Key Details
Gender
All
Age Range
25 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2019-09-26
Completion Date
2023-12-30
Last Updated
2023-01-09
Healthy Volunteers
No
Conditions
Interventions
Nortriptyline + topiramate
Treatment group 1
Verapamil + paroxetine
Treatment group 2
Placebo
Placebo comparator
Locations (1)
University of California, Irvine Medical Center ENT Clinic (Pavilion 2)
Orange, California, United States