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ACTIVE NOT RECRUITING
NCT04406259
PHASE4

Atrioventricular Block and Cluster Headache (SEVA)

Sponsor: Centre Hospitalier Universitaire de Nice

View on ClinicalTrials.gov

Summary

Verapamil is a calcium channel blocker widely used to treat cardiovascular diseases however it is also the first line treatment in the prevention of cluster headaches. In France, its prescription in that indication is based on compliance with the Temporary Recommendation for Use (RTU) that insists on the possible the cardiac side effects that can occur as the doses required for cluster headache are significantly higher than the doses used in cardiology.

Official title: Atrioventricular Block and Cluster Headache

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2020-11-02

Completion Date

2027-09-05

Last Updated

2025-12-02

Healthy Volunteers

No

Interventions

DRUG

Verapamil

Patients in groupe A require verapamil initiation as a preventive treatment and patients in group B are patients already undergoing a verapamil treatment for their Cluster Headache. The doses of verapamil are increased for the patients in group A, after a clinical examination an electrocardiogram, and a blood test.

Locations (2)

CHU de Nice

Nice, CHUN, France

AP-HP Hôpital la Timone

Marseille, France