Clinical Research Directory
Browse clinical research sites, groups, and studies.
Atrioventricular Block and Cluster Headache (SEVA)
Sponsor: Centre Hospitalier Universitaire de Nice
Summary
Verapamil is a calcium channel blocker widely used to treat cardiovascular diseases however it is also the first line treatment in the prevention of cluster headaches. In France, its prescription in that indication is based on compliance with the Temporary Recommendation for Use (RTU) that insists on the possible the cardiac side effects that can occur as the doses required for cluster headache are significantly higher than the doses used in cardiology.
Official title: Atrioventricular Block and Cluster Headache
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2020-11-02
Completion Date
2027-09-05
Last Updated
2025-12-02
Healthy Volunteers
No
Conditions
Interventions
Verapamil
Patients in groupe A require verapamil initiation as a preventive treatment and patients in group B are patients already undergoing a verapamil treatment for their Cluster Headache. The doses of verapamil are increased for the patients in group A, after a clinical examination an electrocardiogram, and a blood test.
Locations (2)
CHU de Nice
Nice, CHUN, France
AP-HP Hôpital la Timone
Marseille, France