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ACTIVE NOT RECRUITING
NCT04415047
NA

The JenaValve ALIGN-AR Pivotal Trial

Sponsor: JenaValve Technology, Inc.

View on ClinicalTrials.gov

Summary

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may include fatigue and shortness of breath. The preferred treatment for severe aortic regurgitation is aortic valve replacement surgery.

Official title: A Study to Assess Safety and Effectiveness of the JenaValve Trilogy™ Heart Valve System in the Treatment of High Surgical Risk Patients With Symptomatic, Severe Aortic Regurgitation (AR)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

180

Start Date

2020-05-22

Completion Date

2028-08

Last Updated

2022-09-13

Healthy Volunteers

No

Interventions

DEVICE

JenaValve Trilogy Heart Valve System

TAVR with JenaValve Trilogy Heart Valve System

Locations (30)

TMC HealthCare & PIMA Heart

Tucson, Arizona, United States

Cedars Sinai Medical Center

Los Angeles, California, United States

Scripps Hospital

San Diego, California, United States

California Pacific Medical Center Research Institute

San Francisco, California, United States

MedStar Washington Hospital Center

Washington D.C., District of Columbia, United States

Morton Plant/ BayCare Health

Clearwater, Florida, United States

Piedmont Healthcare

Atlanta, Georgia, United States

Emory University Hospital

Atlanta, Georgia, United States

Cardiac Surgery Clinical Research Center Inc./ Advocate Aurora Health

Oak Lawn, Illinois, United States

University of Maryland Medical Center

Baltimore, Maryland, United States

University of Michigan

Ann Arbor, Michigan, United States

Henry Ford Health System

Detroit, Michigan, United States

Minneapolis Heart Institute/ Abbott Northwestern

Minneapolis, Minnesota, United States

Barnes-Jewish Hospital / Washington University

St Louis, Missouri, United States

Rutgers Robert Wood Johnson Medical School/ Rutgers Robert Wood University Hospital

Piscataway, New Jersey, United States

New York-Presbyterian/ Columbia University Medical Center

New York, New York, United States

The Christ Hospital

Cincinnati, Ohio, United States

Cleveland Clinic Foundation

Cleveland, Ohio, United States

Ohio Health Research Institute

Columbus, Ohio, United States

Oregon Health & Science University

Portland, Oregon, United States

Allegheny-Singer Health Network

Pittsburgh, Pennsylvania, United States

Lankenau

Wynnewood, Pennsylvania, United States

Medical University of South Carolina

Charleston, South Carolina, United States

Methodist Le Bonheur Healthcare

Memphis, Tennessee, United States

Baylor Scott & White Research Institute

Dallas, Texas, United States

Houston Methodist

Houston, Texas, United States

Memorial Hermann - Texas Medical Center

Houston, Texas, United States

Intermountain Medical Center Heart Institute

Salt Lake City, Utah, United States

Sentara Hospitals

Norfolk, Virginia, United States

University of Washington

Seattle, Washington, United States