Clinical Research Directory
Browse clinical research sites, groups, and studies.
Periinterventional Coagulation Management of Patients Undergoing a TIPS
Sponsor: Medical University of Graz
Summary
Assess whether a pre-interventional thrombelastography guided algorithm for assessing and correction of coagulation status in cirrhotic patients is safe and effective
Official title: Optimizing Periinterventional Coagulation Management of Patients Undergoing a Transjugular Intrahepatic Portosystemic Shunt Implantation: A Prospective Randomized Cohort Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
39
Start Date
2020-05-27
Completion Date
2027-05
Last Updated
2025-12-09
Healthy Volunteers
No
Conditions
Interventions
thrombelastogram
Patients in the TEG group will receive prothrombin complex concentrates (PCC) at a dose of 10 IE/kg of ideal body weight, when R-time was greater than 40 minutes (2400 sec) and they will receive platelet transfusion in the amount of 1 apheresis unit when MA was below 30 mm
standard of care
2\) In the SOC group, patients will receive PCC at the dose of 10 IE /kg of ideal body weight when the PT is below 50% and/or INR\>1.8 and/or received platelet transfusion in the amount of 1 apheresis when platelet count is below 50 G/L
Locations (1)
Department of Internal Medicine, Medical University of Graz
Graz, Austria