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Efficacy and Safety of Cerebrolysin on Prolonged Disorders of Consciousness
Sponsor: Konkuk University Medical Center
Summary
Object: To determine the effect of cerebrolysin on prolonged disorders of consciousness caused by hemorrhagic stroke. Participants: patients with prolonged disorders of consciousness due to severe traumatic brain injury Intervention: 30 ml cerebrolysin + 70 ml normal saline, days 4-17, once/day, intravenously or 100 ml normal saline, days 4-17, once/day, IV Comparison: cerebrolysin group versus control group Outcome: Coma Recovery Scale-revised, FDG-PET signal
Official title: Efficacy and Safety of Cerebrolysin on Prolonged Disorders of Consciousness in Patients With Hemorrhagic Stroke: A Pilot Study
Key Details
Gender
All
Age Range
19 Years - 120 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2023-06-01
Completion Date
2026-12-31
Last Updated
2026-05-11
Healthy Volunteers
No
Interventions
Cerebrolysin
30 ml cerebrolysin + 70 ml normal saline, days 4-17, once/day, intravenously
Control
100 ml normal saline, days 4-17, once/day, IV
Locations (1)
Konkuk University Medical Center Research Coordinating Center
Seoul, South Korea