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Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study
Sponsor: M.D. Anderson Cancer Center
Summary
This study compares the outcomes and safety of two standard treatment options called microwave ablation and surgical wedge resection in patients with non-small cell lung cancer, sarcoma and colorectal cancer that has spread to other parts of the body (metastatic). Microwave ablation is designed to kill tumor cells by heating the tumor until the tumor cells die. A wedge resection is a procedure that involves the surgical removal of a small, wedge-shaped piece of lung tissue to remove a small tumor or to diagnose lung cancer. Comparing these two treatment options may help researchers learn which method works better for the treatment of non-small cell lung cancer, metastatic sarcoma, and metastatic colorectal cancer.
Official title: Ablation of Lung Lesions Using Microwave Energy (ALLUME)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
74
Start Date
2019-08-07
Completion Date
2026-01-01
Last Updated
2025-10-22
Healthy Volunteers
No
Conditions
Interventions
Computed Tomography with Contrast
Undergo contrast-enhanced CT
Microwave Ablation
Undergo microwave ablation
Questionnaire Administration
Ancillary studies
Wedge Excision
Undergo wedge resection
Locations (1)
M D Anderson Cancer Center
Houston, Texas, United States