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NCT04430725

Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study

Sponsor: M.D. Anderson Cancer Center

View on ClinicalTrials.gov

Summary

This study compares the outcomes and safety of two standard treatment options called microwave ablation and surgical wedge resection in patients with non-small cell lung cancer, sarcoma and colorectal cancer that has spread to other parts of the body (metastatic). Microwave ablation is designed to kill tumor cells by heating the tumor until the tumor cells die. A wedge resection is a procedure that involves the surgical removal of a small, wedge-shaped piece of lung tissue to remove a small tumor or to diagnose lung cancer. Comparing these two treatment options may help researchers learn which method works better for the treatment of non-small cell lung cancer, metastatic sarcoma, and metastatic colorectal cancer.

Official title: Ablation of Lung Lesions Using Microwave Energy (ALLUME)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

74

Start Date

2019-08-07

Completion Date

2026-01-01

Last Updated

2025-10-22

Healthy Volunteers

No

Interventions

PROCEDURE

Computed Tomography with Contrast

Undergo contrast-enhanced CT

PROCEDURE

Microwave Ablation

Undergo microwave ablation

OTHER

Questionnaire Administration

Ancillary studies

PROCEDURE

Wedge Excision

Undergo wedge resection

Locations (1)

M D Anderson Cancer Center

Houston, Texas, United States