Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation
Sponsor: Christian Candrian
Summary
We are going to evaluate the difference between perioperative intravenous steroid supplementation, perioperative periarticular steroid supplementation, and standard anaesthesia protocols. We'll evaluate the outcome of patients with knee osteoarthritis who are undergoing Total Knee Arthroplasty to understand which of the three treatments give more benefits to the patient.
Official title: Comparison of Perioperative Intravenous vs Periarticular Dexamethasone vs no Steroid Supplementation in Terms of Post-operative Pain, Function, Nausea, Hospitalization Length, and Risk of Complications in Patients Undergoing Primary Total Knee Arthroplasty for Knee Osteoarthritis - A Randomized Controlled Trial Clinical Study Protocol
Key Details
Gender
All
Age Range
50 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
159
Start Date
2020-07-01
Completion Date
2033-04-30
Last Updated
2025-08-06
Healthy Volunteers
No
Conditions
Interventions
Dexamethasone Sodium Phosphate 4 mg/ml intravenous
Perioperative intravenous injection of 3 ml of solution (9mg of dexamethasone)
Dexamethasone Sodium Phosphate 4 mg/ml intra-articular
Perioperative intra-articular injection of 3 ml of solution (9mg of dexamethasone)
Locations (1)
Ospedale Regionale di Lugano Civico e Italiano
Lugano, Switzerland