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Surfactant Administration by Insure or Thin Catheter
Sponsor: Karolinska Institutet
Summary
This trial evaluates the efficacy and safety of surfactant administration with thin catheter technique together with analgesic premedication in comparison with the established INSURE-strategy. It will provide valuable knowledge to improve clinical methodology and enhance lung protective treatment strategies for preterm infants.
Key Details
Gender
All
Age Range
Any - 2 Days
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2021-05-21
Completion Date
2026-12-31
Last Updated
2025-07-01
Healthy Volunteers
No
Interventions
Thin catheter technique or standard ET-tube for surfactant administration
Surfactant administration by intubation with regular ET-tube followed by immediate extubation to CPAP (INSURE) or by thin catheter during spontaneous breathing and continued CPAP.
Locations (1)
Karolinska University Hospital
Stockholm, Sweden