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Examining Effects of Ocrevus on Cognitive Fatigue Using fMRI
Sponsor: Kessler Foundation
Summary
The purpose of this research study is to investigate the effectiveness of MS Disease modifying medications on cognitive fatigue in persons with relapsing remitting multiple sclerosis (RRMS). Cognitive fatigue is the kind of fatigue that occurs after intense mental concentration as after a session of problem solving.
Official title: A Biomarker for Cognitive Fatigue Using Functional Imaging in MS
Key Details
Gender
All
Age Range
18 Years - 64 Years
Study Type
OBSERVATIONAL
Enrollment
24
Start Date
2021-05-06
Completion Date
2025-10-15
Last Updated
2026-08-11
Healthy Volunteers
Yes
Conditions
Interventions
Ocrevus
Participants with MS will be divided into two treatment groups: those who will begin to take Ocrevus (the "early Ocrevus" group (EO), and those who plan to be begin treatment with Glatimer acetate SC (Copaxone) (EC). Both groups will be matched to the EO group for age, gender and education. The HC group will be free of neurological disease or injury and will be matched to the EO group for age, gender, and education.
Locations (1)
Kessler Foundation
West Orange, New Jersey, United States