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RECRUITING
NCT04449198
EARLY_PHASE1
Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1
Sponsor: Augusta University
View on ClinicalTrials.gov
Summary
The proposed study is designed to test the hypothesis that treatment of resveratrol for 12 weeks will improve both endothelin-B receptor (aim 1) and skeletal muscle mitochondrial function (aim 2) in people with type 1 diabetes.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2020-10-14
Completion Date
2027-07-01
Last Updated
2025-01-28
Healthy Volunteers
Yes
Conditions
Interventions
DRUG
Resveratrol
500 mg of oral trans-resveratrol twice daily (in the morning and evening) for 12-weeks
OTHER
Placebo
placebo for 12 weeks
Locations (1)
Augusta University/Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology
Augusta, Georgia, United States