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RECRUITING
NCT04454203
PHASE4

Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension

Sponsor: Duke University

View on ClinicalTrials.gov

Summary

The goal of this prospective randomized double-blind study is to determine if an ultrasound guided peri-arterial injection of local anesthetic (LA) superomedially the femoral artery via peripheral nerve catheter reverses ischemic hypertension associated with prolonged lower extremity tourniquet time.

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2021-02-05

Completion Date

2027-02-03

Last Updated

2026-03-23

Healthy Volunteers

Yes

Interventions

DRUG

Mepivacaine

An infiltration of mepivacaine superomedially to the femoral artery via perineural catheter.

DRUG

Saline

An infiltration of saline superomedially to the femoral artery via perineural catheter.

PROCEDURE

Perifemoral Injection of Local Anesthetic

Infiltration of mepivacaine superomedially to the formal artery via perineural catheter in an effort to numb the nerves that contribute to tourniquet hypertension intraoperatively.

PROCEDURE

Perifemoral Injection of Local Anesthetic

Infiltration of saline superomedially to the formal artery via perineural catheter that should NOT numb the nerves that contribute to tourniquet hypertension intraoperatively.

Locations (1)

Duke University Hospital

Durham, North Carolina, United States