Clinical Research Directory

Inclusion Criteria: 1. Age ≥ 18 years old, 2. Signed consent to participate, 3. Women with breast cancer over 18 or at high risk of breast cancer (BRCA 1-2 mutations, PALB2, extensive border lesions) 4. Mastectomy with conservation of the areolo-mammary plaque, or mastectomy without conservation of the areolo-mammary plaque and conservation of the skin case 5. Mastectomy without conservation of the areolo-mammary plate, immediate breast reconstruction by prosthesis, 6. immediate breast reconstruction by autologous latissimus dorsi flap 7. immediate breast reconstruction by latissimus dorsi flap and prosthesis, 8. secondary breast reconstruction by latissimus dorsi flap 9. Affiliation to, or beneficiary of, a social security scheme. Exclusion Criteria: 1. Patient under 18, 2. Pregnant woman or likely to be (without effective contraception) or breastfeeding, 3. Person in emergency situation, adult person subject to a legal protection measure (adult under guardianship, curatorship or safeguard of justice), or out of state to express his consent, 4. Inability to submit to medical follow-up for the trial for geographic, social or psychological reasons.