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Prospective Exploratory Study of FAPi PET/CT in Prostate Cancer With Histopathology Validation
Sponsor: Jonsson Comprehensive Cancer Center
Summary
This exploratory study investigates how a new imaging technique called FAPI PET/CT can determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with prostate cancer. Because some cancers take up 68Ga-FAPi-46 it can be seen with PET. FAP stands for Fibroblast Activation Protein. FAP is produced by cells that surround tumors. The function of FAP is not well understood but imaging studies have shown that FAP can be detected with FAPI PET/CT. Imaging FAP with FAPI PET/CT may in the future provide additional information about various cancers including prostate cancer.
Official title: PET Biodistribution Study of 68Ga-FAPI-46 in Patients With Prostate Cancer: A Prospective Exploratory Biodistribution Study With Histopathology Validation
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2020-09-09
Completion Date
2026-05-30
Last Updated
2025-07-15
Healthy Volunteers
No
Conditions
Interventions
Computed Tomography
Undergo PET/CT imaging
Gallium Ga 68 FAPi-46
Given IV
Positron Emission Tomography
Undergo PET/CT imaging
Locations (1)
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States