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68Ga-FAPi-46 PET/CT Scan in Imaging Patients With Sarcoma
Sponsor: Jonsson Comprehensive Cancer Center
Summary
This early phase I trial studies an imaging technique called 68Ga-FAPi-46 PET/CT to determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with sarcoma. PET is an established imaging technique that utilizes small amounts of radioactivity attached to very minimal amounts of tracer, in the case of this research, 68Ga-FAPi. Because some cancers take up 68Ga-FAPi it can be seen with PET. CT utilizes x-rays that traverse body from the outside. CT images provide an exact outline of organs and potential inflammatory tissue where it occurs in patient's body.
Official title: PET Biodistribution Study of 68Ga-FAPI-46 in Patients With Sarcoma: An Exploratory Biodistribution Study With Histopathology Validation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
18
Start Date
2020-09-08
Completion Date
2027-07-21
Last Updated
2025-08-12
Healthy Volunteers
No
Interventions
Computed Tomography
Undergo PET/CT
Gallium Ga 68 FAPi-46
Given IV
Positron Emission Tomography
Undergo PET/CT
18F-FDG
Given IV
Locations (1)
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States