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Evaluation of IRDye800CW-nimotuzumab in Lung Cancer Surgery
Sponsor: University of Saskatchewan
Summary
The purpose of this study is to determine the safety, optimal dose and imaging time of the investigational product, IRDye800CW-nimotuzumab for use as a near infrared imaging probe for image-guided surgery during lung cancer resection. IRDye800CW-nimotuzumab targets cancer cells over-expressing EGFR, allowing tumors to be visualized and may help surgeons better identify cancer during surgery.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2020-09-01
Completion Date
2026-10
Last Updated
2024-01-09
Healthy Volunteers
No
Conditions
Interventions
IRDye800CW-nimotuzumab
50 mg of IRDye800CW-nimotuzumab will be infused intravenously over a period of 30 minutes. Lung cancer resection surgery will be done at different time points post infusion
Locations (1)
St. Paul's Hospital
Saskatoon, Saskatchewan, Canada