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RECRUITING
NCT04459065
PHASE1/PHASE2

Evaluation of IRDye800CW-nimotuzumab in Lung Cancer Surgery

Sponsor: University of Saskatchewan

View on ClinicalTrials.gov

Summary

The purpose of this study is to determine the safety, optimal dose and imaging time of the investigational product, IRDye800CW-nimotuzumab for use as a near infrared imaging probe for image-guided surgery during lung cancer resection. IRDye800CW-nimotuzumab targets cancer cells over-expressing EGFR, allowing tumors to be visualized and may help surgeons better identify cancer during surgery.

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

36

Start Date

2020-09-01

Completion Date

2026-10

Last Updated

2024-01-09

Healthy Volunteers

No

Conditions

Interventions

DRUG

IRDye800CW-nimotuzumab

50 mg of IRDye800CW-nimotuzumab will be infused intravenously over a period of 30 minutes. Lung cancer resection surgery will be done at different time points post infusion

Locations (1)

St. Paul's Hospital

Saskatoon, Saskatchewan, Canada